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The NLRP3 Inflammasome Gene Is Overexpressed in Hidradenitis Suppurativa Lesions: A Preliminary Study on the Role of Pyroptosis in Disease Pathogenesis

Hidradenitis suppurativa (HS) is a debilitating inflammatory skin disorder, and its pathogenesis remains incompletely understood. This study aimed to investigate the role of the P2X7 receptor (P2X7R) and NLRP3 inflammasome in HS pathogenesis. RNA sequencing and real-time PCR were performed to assess...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Hauptverfasser: Piotr K. Krajewski, Weronika Szukała, Jacek C. Szepietowski
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2024-03-01
Schriftenreihe:Current Issues in Molecular Biology
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Online-Zugang:https://www.mdpi.com/1467-3045/46/3/161
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