Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced
Abstract Insulin deficiency in type 1 diabetes (T1D) is generally considered a consequence of immune‐mediated specific beta‐cell loss. Since healthy pancreatic islets consist of ~65% beta cells, this would lead to reduced islet size, while the number of islets per pancreas volume (islet density) wou...
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| Principais autores: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Wiley
2019-10-01
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| Serier: | The Journal of Pathology: Clinical Research |
| Fag: | |
| Online adgang: | https://doi.org/10.1002/cjp2.140 |
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