The traditional chinese medicine monomer Ailanthone improves the therapeutic efficacy of anti-PD-L1 in melanoma cells by targeting c-Jun

Abstract Background C-Jun, a critical component of AP-1, exerts essential functions in various tumors, including melanoma, and is believed to be a druggable target for cancer therapy. Unfortunately, no effective c-Jun inhibitors are currently approved for clinical use. The advent of immune checkpoin...

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Autori principali:	Pian Yu, Hui Wei, Kaixuan Li, Shiguo Zhu, Jie Li, Chao Chen, Detian Zhang, Yayun Li, Lei Zhu, Xiaoqing Yi, Nian Liu, Panpan Liu, Shuang Zhao, Xiang Chen, Cong Peng
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2022-12-01
Serie:	Journal of Experimental & Clinical Cancer Research
Soggetti:	Melanoma Ailanthone PD-L1 c-Jun Treg Tumor microenvironment
Accesso online:	https://doi.org/10.1186/s13046-022-02559-z
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