Genetic Association of Pulmonary Surfactant Protein Genes, SFTPA1, SFTPA2, SFTPB, SFTPC, and SFTPD With Cystic Fibrosis

Surfactant proteins (SP) are involved in surfactant function and innate immunity in the human lung. Both lung function and innate immunity are altered in CF, and altered SP levels and genetic association are observed in Cystic Fibrosis (CF). We hypothesized that single nucleotide polymorphisms (SNPs...

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Autori principali:	Zhenwu Lin, Nithyananda Thorenoor, Rongling Wu, Susan L. DiAngelo, Meixia Ye, Neal J. Thomas, Xiaojie Liao, Tony R. Lin, Stuart Warren, Joanna Floros
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2018-10-01
Serie:	Frontiers in Immunology
Soggetti:	surfactant protein SP-A SP-B SP-C SP-D cystic fibrosis
Accesso online:	https://www.frontiersin.org/article/10.3389/fimmu.2018.02256/full
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