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Znaczenie mechanizmu naprawy DNA błędnie sparowanych zasad azotowych (MMR) w raku piersi

Background: Microsatellite instability (MSI) is due to defective DNA mismatch repair. Defects in DNA mismatch-repair (MMR) genes lead to replication errors revealed as instability in microsatellite markers. Studieshave shown that breast cancer may be associated with mutations in mismatch repair gene...

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Principais autores: Hanna Romanowicz, Beata Smolarz, Tomasz Fiks, Andrzej Kulig, Ireneusz Połać, Anna Sobczuk, Tomasz Pertyński
Formato: Artigo
Idioma:Inglês
Publicado em: Termedia Publishing House 2010-04-01
coleção:Menopause Review
Assuntos:
MMR
DNA repair
breast cancer
Acesso em linha:http://www.termedia.pl/Znaczenie-mechanizmu-naprawy-DNA-blednie-sparowanych-zasad-azotowych-MMR-w-raku-piersi,4,14766,1,0.html
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