Mutual suppression between mutations in the Dictyostelium Greenbeard pathway restores wild-type development

Abstract Background The Dictyostelium greenbeard pathway is mediated by two polymorphic transmembrane proteins, the TgrC1 ligand and the TgrB1 receptor. These proteins mediate allorecognition, altruism, and the developmental transition to multicellularity. A genetic suppressor screen revealed activa...

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Hauptverfasser:	Mariko Katoh-Kurasawa, Lena Trnovec, Peter Lehmann, Blaž Zupan, Gad Shaulsky
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-06-01
Schriftenreihe:	BMC Genomics
Schlagworte:	Mutual suppression Greenbeard pathway Dictyostelium allorecognition Dictyostelium development Transcriptome phenotyping
Online-Zugang:	https://doi.org/10.1186/s12864-025-11745-0
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