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Pyroptosis in Spinal Cord Injury: Implications for Pathogenesis and Therapeutic Approaches

Traumatic spinal cord injury (SCI) is a serious disease of the central nervous system. Aside from the limited intrinsic regenerative capacity of neurons, complex microenvironmental disturbances can also lead to further cellular damage and growth inhibition. Programmed cell death regulated by pyropto...

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Main Authors: Guangjin Gu, Huaqi Yu, Huishuang Zou, Wenjuan Kou, Pingping Zhang, Guangjie Gu, Jie Lu, Weihan Shi, Pengcheng Chu, Yaning Zhang, Guangwei Sun, Jun Shang
Format: Artigo
Language:Inglês
Published: IMR Press 2024-06-01
Series:Frontiers in Bioscience-Landmark
Subjects:
spinal cord injury
pyroptosis
gasdermin d
inflammasome
nlrp3
Online Access:https://www.imrpress.com/journal/FBL/29/6/10.31083/j.fbl2906210
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