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<i>N</i>-Acetylcysteine in Mechanically Ventilated Rats with Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome: The Effect of Intravenous Dose on Oxidative Damage and Inflammation

Treatment of acute respiratory distress syndrome (ARDS) is challenging due to its multifactorial aetiology. The benefit of antioxidant therapy was not consistently demonstrated by previous studies. We evaluated the effect of two different doses of intravenous (i.v.) <i>N</i>-acetylcysteine (NAC) on...

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Autori principali: Maros Kolomaznik, Pavol Mikolka, Juliana Hanusrichterova, Petra Kosutova, Katarina Matasova, Daniela Mokra, Andrea Calkovska
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2021-12-01
Serie:Biomedicines
Soggetti:
ARDS
bacterial lipopolysaccharide
<i>N</i>-acetylcysteine
lung functions parameters
inflammation
oxidative damage
Accesso online:https://www.mdpi.com/2227-9059/9/12/1885
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