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Master Sculptor at Work: Enteropathogenic Escherichia coli Infection Uniquely Modifies Mitochondrial Proteolysis during Its Control of Human Cell Death

ABSTRACT Enteropathogenic Escherichia coli (EPEC) causes severe diarrheal disease and is present globally. EPEC virulence requires a bacterial type III secretion system to inject >20 effector proteins into human intestinal cells. Three effectors travel to mitochondria and modulate apoptosis; however...

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Autors principals: Natalie C. Marshall, Maichael Thejoe, Theo Klein, Antonio Serapio-Palacios, Andrew S. Santos, Niklas von Krosigk, Jayachandran N. Kizhakkedathu, Nikolay Stoynov, Leonard J. Foster, Christopher M. Overall, B. Brett Finlay
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020-06-01
Col·lecció:mSystems
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Accés en línia:https://journals.asm.org/doi/10.1128/msystems.00283-20
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