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Heat-shock protein 90 promotes nuclear transport of herpes simplex virus 1 capsid protein by interacting with acetylated tubulin.

Although it is known that inhibitors of heat shock protein 90 (Hsp90) can inhibit herpes simplex virus type 1 (HSV-1) infection, the role of Hsp90 in HSV-1 entry and the antiviral mechanisms of Hsp90 inhibitors remain unclear. In this study, we found that Hsp90 inhibitors have potent antiviral activ...

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Auteurs principaux: Meigong Zhong, Kai Zheng, Maoyun Chen, Yangfei Xiang, Fujun Jin, Kaiqi Ma, Xianxiu Qiu, Qiaoli Wang, Tao Peng, Kaio Kitazato, Yifei Wang
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2014-01-01
Collection:PLoS ONE
Accès en ligne:http://europepmc.org/articles/PMC4047101?pdf=render
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