A Central Role for Atg5 in Microbiota-Dependent Foxp3+ RORγt+ Treg Cell Preservation to Maintain Intestinal Immune Homeostasis

Autophagy is an evolutionary conserved catabolic pathway that ensures the degradation of intracellular components. The autophagic pathway is regulated by autophagy-related (Atg) proteins that govern formation of double-membraned vesicles called autophagosomes. Autophagy deficiency in regulatory T (T...

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Hlavní autoři:	Carlos Plaza-Sirvent, Bei Zhao, Alisha W. Bronietzki, Marina C. Pils, Neda Tafrishi, Marc Schuster, Till Strowig, Ingo Schmitz
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2021-08-01
Edice:	Frontiers in Immunology
Témata:	autophagy Atg5 RORγt+ Foxp3+ Treg cells intestinal homeostasis inflammation
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.705436/full
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