Differential activation of the death receptor pathway in human target cells induced by cytotoxic T lymphocytes showing different kinetics of killing

Background and Objectives Cytotoxic T lymphocytes (CTL) may use two effector mechanisms to kill their target cells: perforin (PFN) and granzyme B (GrB)-dependent granule-mediated cell death and death receptor-mediated cell death. Controversy exists whether, in addition to PFN/GrB-mediated apoptosis,...

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Prif Awduron:	Jeltje F. de Vries, Peter A. von dem Borne, Simone A.P. van Luxemburg-Heijs, Mirjam H.M. Heemskerk, Roel Willemze, J.H. Frederik Falkenburg, Renèe M.Y. Barge
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Ferrata Storti Foundation 2007-12-01
Cyfres:	Haematologica
Mynediad Ar-lein:	https://haematologica.org/article/view/4668
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