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Identification of key residues that confer Rhodobacter sphaeroides LPS activity at horse TLR4/MD-2.

The molecular determinants underpinning how hexaacylated lipid A and tetraacylated precursor lipid IVa activate Toll-like receptor 4 (TLR4) are well understood, but how activation is induced by other lipid A species is less clear. Species specificity studies have clarified how TLR4/MD-2 recognises d...

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Váldodahkkit: Katherine L Irvine, Monique Gangloff, Catherine M Walsh, David R Spring, Nicholas J Gay, Clare E Bryant
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2014-01-01
Ráidu:PLoS ONE
Liŋkkat:https://doi.org/10.1371/journal.pone.0098776
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