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Heat shock-induced chaperoning by Hsp70 is enabled in-cell.

Recent work has shown that weak protein-protein interactions are susceptible to the cellular milieu. One case in point is the binding of heat shock proteins (Hsps) to substrate proteins in cells under stress. Upregulation of the Hsp70 chaperone machinery at elevated temperature was discovered in the...

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Principais autores: Drishti Guin, Hannah Gelman, Yuhan Wang, Martin Gruebele
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Acceso en liña:https://doi.org/10.1371/journal.pone.0222990
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