Clinicopathological and molecular characterization of tumor-associated macrophages in sporadic and Xeroderma Pigmentosum-related cutaneous melanoma

Abstract Background Xeroderma pigmentosum (XP) is a rare autosomal recessive disorder, resulting from genetic defects in the nucleotide excision repair (NER) pathway. It predisposes individuals to skin cancers, including melanoma. The melanoma microenvironment is enriched with inflammatory mediators...

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Autors principals:	Asma Chikhaoui, Haifa Tounsi, Imen Nabouli, Mariem Jones, Rim Jenni, Malika Ben Ahmed, Chokri Naouali, Mohammed Zghal, Hamida Turki, Houda Yacoub-Youssef
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2026-04-01
Col·lecció:	BMC Cancer
Matèries:	IL-33 Cutaneous malignant melanoma Tumor-associated macrophage Xeroderma Pigmentosum
Accés en línia:	https://doi.org/10.1186/s12885-026-15966-8
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