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Anti-apoptotic BCL2L2 increases megakaryocyte proplatelet formation in cultures of human cord blood

Apoptosis is a recognized limitation to generating large numbers of megakaryocytes in culture. The genes responsible have been rigorously studied in vivo in mice, but are poorly characterized in human culture systems. As CD34-positive (+) cells isolated from human umbilical vein cord blood were diff...

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Bibliografiske detaljer
Principais autores: Seema Bhatlekar, Indranil Basak, Leonard C. Edelstein, Robert A. Campbell, Cory R. Lindsey, Joseph E. Italiano, Andrew S. Weyrich, Jesse W. Rowley, Matthew T. Rondina, Martha Sola-Visner, Paul F. Bray
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2019-10-01
Serier:Haematologica
Online adgang:https://haematologica.org/article/view/9090
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