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RNA-seq and Tn-seq reveal fitness determinants of vancomycin-resistant Enterococcus faecium during growth in human serum

Abstract Background The Gram-positive bacterium Enterococcus faecium is a commensal of the human gastrointestinal tract and a frequent cause of bloodstream infections in hospitalized patients. The mechanisms by which E. faecium can survive and grow in blood during an infection have not yet been char...

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Principais autores: Xinglin Zhang, Vincent de Maat, Ana M. Guzmán Prieto, Tomasz K. Prajsnar, Jumamurat R. Bayjanov, Mark de Been, Malbert R. C. Rogers, Marc J. M. Bonten, Stéphane Mesnage, Rob J. L. Willems, Willem van Schaik
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2017-11-01
Serier:BMC Genomics
Fag:
Enterococcus faecium
Transcriptome
Transposon mutant library screening
Nucleotide biosynthesis
Carbohydrate metabolism
Virulence
Online adgang:http://link.springer.com/article/10.1186/s12864-017-4299-9
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