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Potential Role of Mic60/Mitofilin in Parkinson’s Disease

There are currently no treatments that hinder or halt the inexorable progression of Parkinson’s disease (PD). While the etiology of PD remains elusive, evidence suggests that early dysfunction of mitochondrial respiration and homeostasis play a major role in PD pathogenesis. The mitochondrial struct...

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Principais autores: Victor S. Van Laar, P. Anthony Otero, Teresa G. Hastings, Sarah B. Berman
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019-01-01
Serier:Frontiers in Neuroscience
Fag:
Mic60/mitofilin
mitochondria
Parkinson’s disease
neurodegeneration
mitochondrial dynamics
Online adgang:https://www.frontiersin.org/article/10.3389/fnins.2018.00898/full
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