Transcriptomic analysis identifies lactoferrin-induced quiescent circuits in neonatal macrophages

IntroductionUpon birth, a hitherto naïve immune system is confronted with a plethora of microbial antigens due to intestinal bacterial colonization. To prevent excessive inflammation and disruption of the epithelial barrier, physiological mechanisms must promote immune-anergy within the neonatal gut...

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Principais autores:	Michael Eigenschink, Isabelle Wessely, Marco Dijmarescu, Elisabeth Förster-Waldl, Alex Farr, Herbert Kiss, Angelika Berger, Lukas Wisgrill
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-10-01
coleção:	Frontiers in Immunology
Assuntos:	human lactoferrin neonatal immune system immune tolerance macrophage function microbiome necrotizing enterocolitis
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1276173/full
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