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Angiopoietin-1 Mimetic Nanoparticles for Restoring the Function of Endothelial Cells as Potential Therapeutic for Glaucoma

A root cause for the development and progression of primary open-angle glaucoma might be the loss of the Schlemm’s canal (SC) cell function due to an impaired Angiopoietin-1 (Angpt-1)/Tie2 signaling. Current therapeutic options fail to restore the SC cell function. We propose Angpt-1 mimetic nanopar...

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Principais autores: Raphael Mietzner, Ramona Pawlak, Ernst R. Tamm, Achim Goepferich, Rudolf Fuchshofer, Miriam Breunig
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2021-12-01
Series:Pharmaceuticals
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Acceso en liña:https://www.mdpi.com/1424-8247/15/1/18
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