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Design, synthesis, and insilico evaluation of 2-aminothiazole derivatives as potential mTOR and EGFR inhibitors

Abstract A series of 14 novel 2-aminothiazole (1a-1 g, 2a-2 g) derivatives were synthesized effectively and in silico evaluation was performed to find lead candidates as potential inhibitors targeting breast cancer receptors. One-pot three-component synthesis was carried out using different methods,...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Pramod Mallikarjuna Swamy, Preetham Harave Somashekar, Santhosh Arehalli Shivamurthy, Sandeep Shadakshari, Mallu Puttaswamappa, Nanjunda Swamy Shanthappa
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Springer Nature 2025-12-01
Rangatū:Discover Molecules
Ngā marau:
Urunga tuihono:https://doi.org/10.1007/s44345-025-00039-3
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