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The “window of susceptibility” for inflammation in the immature central nervous system is characterized by a leaky blood–brain barrier and the local expression of inflammatory chemokines

Early in postnatal development, the immature central nervous system (CNS) is more susceptible to inflammation than its adult counterpart. We show here that this “window of susceptibility” is characterized by the presence of leaky vessels in the CNS, and by a global chemokine expression profile which...

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Váldodahkkit: Lucia Schoderboeck, Milena Adzemovic, Eva-Maria Nicolussi, Claudia Crupinschi, Sonja Hochmeister, Marie-Therese Fischer, Hans Lassmann, Monika Bradl
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Elsevier 2009-09-01
Ráidu:Neurobiology of Disease
Fáttát:
Liŋkkat:http://www.sciencedirect.com/science/article/pii/S0969996109001296
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