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Distribution of Cardiac and Renal Corin and Proprotein Convertase Subtilisin/Kexin-6 in the Experimental Model of Cardio-Renal Syndrome of Various Severities

Congestive heart failure (CHF) often leads to progressive cardiac hypertrophy and salt/water retention. However, its pathogenesis remains largely unclarified. Corin, a cardiac serine protease, is responsible for converting proANP and proBNP to biologically active peptides. Although the involvement o...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Emad E. Khoury, Ahmad Fokra, Safa Kinaneh, Yara Knaney, Doron Aronson, Zaid Abassi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021-10-01
Schriftenreihe:Frontiers in Physiology
Schlagworte:
corin
PCSK6
natriuretic peptides
furin
cardiorenal syndrome
heart
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fphys.2021.673497/full
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