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Dental follicle cell differentiation towards periodontal ligament-like tissue in a self-assembly three-dimensional organoid model

Periodontitis remains an unsolved oral disease, prevalent worldwide and resulting in tooth loss due to dysfunction of the periodontal ligament (PDL), a tissue connecting the tooth root with the alveolar bone. A scaffold-free three-dimensional (3D) organoid model for in vitro tenogenesis/ligamentogen...

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Principais autores: J Chu, O Pieles, CG Pfeifer, V Alt, C Morsczeck, D Docheva
Format: Artigo
Sprog:Inglês
Udgivet: Forum Multimedia Publishing LLC 2021-07-01
Serier:European Cells & Materials
Fag:
periodontitis
periodontal ligament
dental follicle cells
periodontal ligament cell line
scaffold-free approach
3d organoids
ligamentogenic differentiation
tissue engineering
Online adgang:https://www.ecmjournal.org/papers/vol042/pdf/v042a02.pdf
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