The human orphan nuclear receptor tailless (TLX, NR2E1) is druggable.

Nuclear receptors (NRs) are an important group of ligand-dependent transcriptional factors. Presently, no natural or synthetic ligand has been identified for a large group of orphan NRs. Small molecules to target these orphan NRs will provide unique resources for uncovering regulatory systems that i...

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Bibliografski detalji

Glavni autori:	Cindy Benod, Rosa Villagomez, Carly S Filgueira, Peter K Hwang, Paul G Leonard, Guillaume Poncet-Montange, Senapathy Rajagopalan, Robert J Fletterick, Jan-Åke Gustafsson, Paul Webb
Format:	Artigo
Jezik:	Inglês
Izdano:	Public Library of Science (PLoS) 2014-01-01
Serija:	PLoS ONE
Online pristup:	http://europepmc.org/articles/PMC4060991?pdf=render
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