WD40 domain divergence is important for functional differences between the fission yeast Tup11 and Tup12 co-repressor proteins.
We have previously demonstrated that subsets of Ssn6/Tup target genes have distinct requirements for the Schizosaccharomyces pombe homologs of the Tup1/Groucho/TLE co-repressor proteins, Tup11 and Tup12. The very high level of divergence in the histone interacting repression domains of the two prote...
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| Principais autores: | , , , |
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| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
Public Library of Science (PLoS)
2010-06-01
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| 丛编: | PLoS ONE |
| 在线阅读: | http://europepmc.org/articles/PMC2882346?pdf=render |
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