TRIM21‐Promoted FSP1 Plasma Membrane Translocation Confers Ferroptosis Resistance in Human Cancers

Abstract Ferroptosis, an iron‐dependent form of regulated cell death driven by excessive accumulation of lipid peroxides, has become a promising strategy in cancer treatment. Cancer cells exploit antioxidant proteins, including Ferroptosis Suppressor Protein 1 (FSP1), to prevent ferroptosis. In this...

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Bibliografiske detaljer

Principais autores:	Jun Gong, Yuhui Liu, Wenjia Wang, Ruizhi He, Qilong Xia, Lin Chen, Chunle Zhao, Yang Gao, Yongkang Shi, Yu Bai, Yangwei Liao, Qi Zhang, Feng Zhu, Min Wang, Xu Li, Renyi Qin
Format:	Artigo
Sprog:	Inglês
Udgivet:	Wiley 2023-10-01
Serier:	Advanced Science
Fag:	cancer ferroptosis FSP1 TRIM21 ubiquitination
Online adgang:	https://doi.org/10.1002/advs.202302318
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