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Biphasic euchromatin-to-heterochromatin transition on the KSHV genome following de novo infection.

The establishment of latency is an essential step for the life-long persistent infection and pathogenesis of Kaposi's sarcoma-associated herpesvirus (KSHV). While the KSHV genome is chromatin-free in the virions, the viral DNA in latently infected cells has a chromatin structure with activating and...

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Autors principals: Zsolt Toth, Kevin Brulois, Hye-Ra Lee, Yoshihiro Izumiya, Clifford Tepper, Hsing-Jien Kung, Jae U Jung
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2013-01-01
Col·lecció:PLoS Pathogens
Accés en línia:http://europepmc.org/articles/PMC3868514?pdf=render
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