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WTAP modulates macrophage polarization in rheumatoid arthritis by targeting exosomal circ-CBLB via m6A modification

IntroductionInteractions between fibroblast-like synoviocytes (FLSs) and macrophages are pivotal in the pathogenesis of rheumatoid arthritis (RA). Exosomal circular RNAs (circRNAs) are key players in the communication between RA-FLSs and macrophages, yet their specific roles in RA pathogenesis remai...

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Hlavní autoři: Dawei Yan, Lei Wan
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2025-06-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1601259/full
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