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Alterations of plasma lipids in mice via adenoviral-mediated hepatic overexpression of human ABCA1

ATP binding cassette transporter A1 (ABCA1) is a widely expressed lipid transporter essential for the generation of HDL. ABCA1 is particularly abundant in the liver, suggesting that the liver may play a major role in HDL homeostasis. To determine how hepatic ABCA1 affects plasma HDL cholesterol leve...

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Principais autores: Cheryl L. Wellington, Liam R. Brunham, Steven Zhou, Roshni R. Singaraja, Henk Visscher, Allison Gelfer, Colin Ross, Erick James, Guoqing Liu, Mary T. Huber, Yu-Zhou Yang, Robin J. Parks, Albert Groen, Jamila Fruchart-Najib, Michael R. Hayden
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2003-08-01
Serier:Journal of Lipid Research
Fag:
ATP binding cassette transporter A1
HDL cholesterol
adenovirus
bacterial artificial chromosome transgenic
hepatocytes
regulation
Online adgang:http://www.sciencedirect.com/science/article/pii/S002222752033755X
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