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Membrane and Protein Interactions of the Pleckstrin Homology Domain Superfamily

The human genome encodes about 285 proteins that contain at least one annotated pleckstrin homology (PH) domain. As the first phosphoinositide binding module domain to be discovered, the PH domain recruits diverse protein architectures to cellular membranes. PH domains constitute one of the largest...

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Gardado en:
Principais autores: Marc Lenoir, Irina Kufareva, Ruben Abagyan, Michael Overduin
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2015-10-01
Series:Membranes
Assuntos:
bilayer insertion
lipid binding
membrane trafficking
MODA
peripheral membrane protein
PH domain
phosphoinositide recognition
plasma membrane
pleckstrin homology domain
small GTPase
Acceso en liña:http://www.mdpi.com/2077-0375/5/4/646
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