Radial Flow Perfusion Enables Real-Time Profiling of Cellular Metabolism at Low Oxygen Levels with Hyperpolarized ¹³C NMR Spectroscopy

In this study, we describe new methods for studying cancer cell metabolism with hyperpolarized ¹³C magnetic resonance spectroscopy (HP ¹³C MRS) that will enable quantitative studies at low oxygen concentrations. Cultured hepatocellular carcinoma cells were grown on the surfaces...

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Autors principals:	Anthony Mancuso, Mehrdad Pourfathi, Ryan M. Kiefer, Michael C. Noji, Sarmad Siddiqui, Enri Profka, Charles N. Weber, Austin Pantel, Stephen J. Kadlecek, Rahim Rizi, Terence P. F. Gade
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2021-08-01
Col·lecció:	Metabolites
Matèries:	hyperpolarized <sup>13</sup>C DNP NMR spectroscopy radial flow oxygen transport perfusion
Accés en línia:	https://www.mdpi.com/2218-1989/11/9/576
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