Chikungunya Virus Strains Show Lineage-Specific Variations in Virulence and Cross-Protective Ability in Murine and Nonhuman Primate Models

ABSTRACT Chikungunya virus (CHIKV) is a reemerging arbovirus capable of causing explosive outbreaks of febrile illness, polyarthritis, and polyarthralgia, inflicting severe morbidity on affected populations. CHIKV can be genetically classified into 3 major lineages: West African (WA); East, Central,...

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Principais autores:	Rose M. Langsjoen, Sherry L. Haller, Chad J. Roy, Heather Vinet-Oliphant, Nicholas A. Bergren, Jesse H. Erasmus, Jill A. Livengood, Tim D. Powell, Scott C. Weaver, Shannan L. Rossi
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology 2018-05-01
Serija:	mBio
Teme:	alphavirus chikungunya vaccine
Online dostop:	https://journals.asm.org/doi/10.1128/mBio.02449-17
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