Targeted Lymph Node Immunization with Serotype-Specific Dengue VLP Vaccines Enhances Antibody Avidity and Specificity

Introduction: Dengue virus (DENV) remains a global health threat, with four distinct serotypes (DENV1-4) that complicate vaccine development due to low-affinity, cross-reactive antibodies that increase the risk of antibody-dependent enhancement (ADE). Objective: To address the challenge of inducing...

Description complète

Détails bibliographiques

Auteurs principaux:	Dominik A. Rothen, Alessandro Pardini, Sudip Kumar Dutta, Pascal S. Krenger, Anne-Cathrine Vogt, Romano Josi, Monique Vogel, Paul Engeroff, Mona O. Mohsen, Kaspars Tars, Byron Martina, Martin F. Bachmann
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2025-09-01
Collection:	Vaccines
Sujets:	dengue vaccine lymph node virus flaviviruses virus-like particle
Accès en ligne:	https://www.mdpi.com/2076-393X/13/9/941
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!