Generation of functional salivary gland tissue from human submandibular gland stem/progenitor cells

Abstract Background Organ replacement regenerative therapy based on human adult stem cells may be effective for salivary gland hypofunction. However, the generated tissues are immature because the signaling factors that induce the differentiation of human salivary gland stem cells into salivary glan...

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Principais autores:	Yi Sui, Siqi Zhang, Yongliang Li, Xin Zhang, Waner Hu, Yanrui Feng, Jingwei Xiong, Yuanyuan Zhang, Shicheng Wei
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2020-03-01
Series:	Stem Cell Research & Therapy
Assuntos:	Human salivary gland stem cells Organoids Salivary gland regeneration Xerostomia FGF10 Mouse embryonic salivary gland mesenchyme
Acceso en liña:	http://link.springer.com/article/10.1186/s13287-020-01628-4
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