Bone Morphogenetic Protein-4 Impairs Retinal Endothelial Cell Barrier, a Potential Role in Diabetic Retinopathy

Bone Morphogenetic Protein 4 (BMP4) is a secreted growth factor of the Transforming Growth Factor beta (TGFβ) superfamily. The goal of this study was to test whether BMP4 contributes to the pathogenesis of diabetic retinopathy (DR). Immunofluorescence of BMP4 and the vascular marker isolectin-B4 was...

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Autores principales:	Noureldien H. E. Darwish, Khaled A. Hussein, Khaled Elmasry, Ahmed S. Ibrahim, Julia Humble, Mohamed Moustafa, Fatma Awadalla, Mohamed Al-Shabrawey
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2023-04-01
Colección:	Cells
Materias:	bone morphogenetic proteins BMP4 Smad1/5/9 diabetic retinopathy blood–retinal barrier function
Acceso en línea:	https://www.mdpi.com/2073-4409/12/9/1279
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