Exploring the Synthetic Potential of γ-Lactam Derivatives Obtained from a Multicomponent Reaction—Applications as Antiproliferative Agents

A study on the reactivity of 3-amino α,β-unsaturated γ-lactam derivatives obtained from a multicomponent reaction is presented. Key features of the substrates are the presence of an endocyclic α,β-unsaturated amide moiety and an enamine functionality. Following different synthetic protocols, the fun...

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Autori principali:	Adrián López-Francés, Xabier del Corte, Zuriñe Serna-Burgos, Edorta Martínez de Marigorta, Francisco Palacios, Javier Vicario
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2022-06-01
Serie:	Molecules
Soggetti:	multicomponent synthesis γ-lactams regioselective functionalization antiproliferative effect
Accesso online:	https://www.mdpi.com/1420-3049/27/11/3624
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