Robust drug bioavailability and safety for rheumatoid arthritis therapy using D-amino acids-based supramolecular hydrogels

Long-term use of disease-modifying anti-rheumatic drugs (DMARDs) such as methotrexate (MTX) shows clinical benefits for rheumatoid arthritis (RA) treatment. However, there are growing concerns over the adverse effects of systemic drug administration. Therefore, a strategy that can enhance drug bioav...

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Autori principali:	Shaodan Ma, Shunan Gu, Jinwei Zhang, Weizhong Qi, Zhaowei Lin, Weicheng Zhai, Jie Zhan, Qi Li, Yanbin Cai, Yao Lu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2022-06-01
Serie:	Materials Today Bio
Soggetti:	Rheumatoid arthritis Supramolecular hydrogel d-amino acids Methotrexate Drug delivery system
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2590006422000941
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