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JC virus detection and JC virus-specific immunity in natalizumab-treated Multiple Sclerosis patients

<p>Abstract</p> <p>Background</p> <p>The use of natalizumab in multiple sclerosis (MS) may favour JC virus reactivation; this phenomenon is usually asymptomatic but can, albeit rarely, evolve into frank progressive multifocal leucoencephalopathy (PML).</p> <p>Methods</p> <p>JCV-specific CD8+ T lymph...

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Principais autores: Mancuso Roberta, Saresella Marina, Hernis Ambra, Marventano Ivana, Ricci Cristian, Agostini Simone, Rovaris Marco, Caputo Domenico, Clerici Mario
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2012-12-01
Serier:Journal of Translational Medicine
Fag:
Cell mediated immunity
Natalizumab
MS
Online adgang:http://www.translational-medicine.com/content/10/1/248
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