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Computational limitations and future needs to unravel the full potential of 2’-O-methylation and C/D box snoRNAs

This review evaluates the current state of C/D snoRNA databases and prediction tools in relation to 2’-O-methylation (2'-O-Me). It highlights the limitations of existing resources in accurately annotating and predicting guide snoRNAs, particularly for newly identified 2’-O-Me sites. We emphasize the...

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Furkejuvvon:
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Váldodahkkit: Christian Ramirez, Elena Perenthaler, Fabio Lauria, Toma Tebaldi, Gabriella Viero
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Taylor & Francis Group 2025-12-01
Ráidu:RNA Biology
Fáttát:
Liŋkkat:https://www.tandfonline.com/doi/10.1080/15476286.2025.2506712
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