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Multifaceted role of Iroquois signaling in development and diseases

ABSTRACT: The Iroquois (Iro/Irx) gene family encodes transcription factors that belong to the Three-Amino-Acid Loop Extension-class homeodomain group, distinguished by a conserved Iro-box domain. Iroquois signaling is evolutionarily conserved from invertebrates to vertebrates and plays a vital role...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Ravi Shankar Goutam, Neha Kaushik, Basant Kumar, Woochan Jung, Santosh Kumar, Seung-Hwan Lee, Unjoo Lee, Jaebong Kim
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2025-12-01
Schriftenreihe:Molecules and Cells
Schlagworte:
Three-amino-acid loop extension homeodomain
Iroquois genes
Embryonic development
Cancer
Congenital heart disease
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S1016847825001207
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