Population-based BRCA germline mutation screening in the Han Chinese identifies individuals at risk of BRCA mutation-related cancer: experience from a clinical diagnostic center from greater Shanghai area

Abstract Background Deleterious BRCA1/2 (BRCA) mutation raises the risk for BRCA mutation-related malignancies, including breast, ovarian, prostate, and pancreatic cancer. Germline variation of BRCA exhibits substantial ethnical diversity. However, there is limited research on the Chinese Han popula...

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Główni autorzy:	Zhiyuan Wu, Qingyun Zhang, Yiting Jin, Xinju Zhang, Yanli Chen, Can Yang, Xuemei Tang, Haowen Jiang, Xiaoyi Wang, Xinli Zhou, Feng Yu, Bing Wang, Ming Guan
Format:	Artigo
Język:	Inglês
Wydane:	BMC 2024-04-01
Seria:	BMC Cancer
Hasła przedmiotowe:	BRCA mutation related-cancer Germline mutation Population screening
Dostęp online:	https://doi.org/10.1186/s12885-024-12089-w
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