Viral Envelope Evolution in Simian–HIV-Infected Neonate and Adult-Dam Pairs of Rhesus Macaques

We recently demonstrated that Simian–HIV (SHIV)-infected neonate rhesus macaques (RMs) generated heterologous HIV-1 neutralizing antibodies (NAbs) with broadly-NAb (bNAb) characteristics at a higher frequency compared with their corresponding dam. Here, we characterized genetic diversity in Env sequ...

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主要な著者:	Elena E. Giorgi, Hui Li, Bhavna Hora, George M. Shaw, Kshitij Wagh, Wilton B. Williams
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2024-06-01
シリーズ:	Viruses
主題:	viral Env evolution dam–neonate infection pairs macaque SHIV infection neonatal SHIV immunity antibody–virus coevolution NAb selection pressures on HIV-1 Env
オンライン･アクセス:	https://www.mdpi.com/1999-4915/16/7/1014
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