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Modulatory effects of the antioxidant ascorbic acid on the direct genotoxicity of doxorubicin in somatic cells of Drosophila melanogaster

In this study two different crosses involving the wing cell markers mwh and flr³ (standard (ST) cross and high bioactivation (HB) cross, the latter being characterized by a high constitutive level of cytochrome P450 which leads to an increased sensitivity to a number of promutagens and procarcinogen...

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Principais autores: Edson José Fragiorge, Mário Antônio Spanó, Lusânia Maria Greggi Antunes
Format: Artigo
Jezik:Inglês
Izdano: Sociedade Brasileira de Genética 2007-03-01
Serija:Genetics and Molecular Biology
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Online dostop:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572007000300025
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