A-to-I editing in human miRNAs is enriched in seed sequence, influenced by sequence contexts and significantly hypoedited in glioblastoma multiforme

Abstract Editing in microRNAs, particularly in seed can significantly alter the choice of their target genes. We show that out of 13 different human tissues, different regions of brain showed higher adenosine to inosine (A-to-I) editing in mature miRNAs. These events were enriched in seed sequence (...

Fuld beskrivelse

Bibliografiske detaljer

Principais autores:	Deepanjan Paul, Ashis Narayan Sinha, Arjun Ray, Megha Lal, Subhashree Nayak, Anchal Sharma, Bharati Mehani, Debasish Mukherjee, Saurabh V. Laddha, Ashish Suri, Chitra Sarkar, Arijit Mukhopadhyay
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2017-05-01
Serier:	Scientific Reports
Online adgang:	https://doi.org/10.1038/s41598-017-02397-6
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!