The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice

Abstract Background The gut microbiota–intestine–liver relationship is emerging as an important factor in multiple hepatic pathologies, but the hepatic sensors and effectors of microbial signals are not well defined. Results By comparing publicly available liver transcriptomics data from conventiona...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Sharon Ann Barretto, Frederic Lasserre, Marine Huillet, Marion Régnier, Arnaud Polizzi, Yannick Lippi, Anne Fougerat, Elodie Person, Sandrine Bruel, Colette Bétoulières, Claire Naylies, Céline Lukowicz, Sarra Smati, Laurence Guzylack, Maïwenn Olier, Vassilia Théodorou, Laila Mselli-Lakhal, Daniel Zalko, Walter Wahli, Nicolas Loiseau, Laurence Gamet-Payrastre, Hervé Guillou, Sandrine Ellero-Simatos
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2021-04-01
סדרה:	Microbiome
נושאים:	Gut microbiota Liver Pregnane X receptor NR1I2 Xenobiotic metabolism Fatty acid metabolism
גישה מקוונת:	https://doi.org/10.1186/s40168-021-01050-9
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!