Impairing hydrolase transport machinery prevents human melanoma metastasis
Abstract Metastases are the major cause of cancer-related death, yet, molecular weaknesses that could be exploited to prevent tumor cells spreading are poorly known. Here, we found that perturbing hydrolase transport to lysosomes by blocking either the expression of IGF2R, the main receptor responsi...
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| Principais autores: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2024-05-01
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| coleção: | Communications Biology |
| Acesso em linha: | https://doi.org/10.1038/s42003-024-06261-y |
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