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Desmin Modulates Muscle Cell Adhesion and Migration

Cellular adhesion and migration are key functions that are disrupted in numerous diseases. We report that desmin, a type-III muscle-specific intermediate filament, is a novel cell adhesion regulator. Expression of p.R406W mutant desmin, identified in patients with desmin-related myopathy, modified f...

Deskribapen osoa

Gorde:
Egile Nagusiak: Coralie Hakibilen, Florence Delort, Marie-Thérèse Daher, Pierre Joanne, Eva Cabet, Olivier Cardoso, Fany Bourgois-Rocha, Cuixia Tian, Eloy Rivas, Marcos Madruga, Ana Ferreiro, Alain Lilienbaum, Patrick Vicart, Onnik Agbulut, Sylvie Hénon, Sabrina Batonnet-Pichon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2022-03-01
Saila:Frontiers in Cell and Developmental Biology
Gaiak:
desmin
vinculin
focal adhesion
migration
myopathies
intermediate filaments
Sarrera elektronikoa:https://www.frontiersin.org/articles/10.3389/fcell.2022.783724/full
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