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Growth Hormone Promotes Lipolysis and Impairs Insulin Sensitivity by Activating the ERK/HSL Signaling Pathway in Bovine Adipocytes

ABSTRACT The physiological adaptation responses of peripartum cows to negative energy balance, including fat mobilization and insulin resistance, are controlled by hormones. Excessive growth hormone (GH) promotes fat mass loss and insulin resistance in nonruminants. Despite elevated circulating GH i...

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Principais autores: Xinxing Gao, Hao Yu, Erminio Trevisi, Cai Lin, Zhiyuan Fang, Xinwei Li, Yuxiang Song, Wenwen Gao, Lin Lei, Xiliang Du, Guowen Liu
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2026-05-01
Serier:Animal Research and One Health
Fag:
adipocytes
dairy cow
growth hormone
insulin resistance
lipid mobilization
Online adgang:https://doi.org/10.1002/aro2.70015
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