Mitochondria-targeted strategies in cancer radiotherapy: from ROS regulation to immunogenic cell death

Radiotherapy (RT) is a crucial treatment modality for various solid tumors. Its antitumor effects not only depend on direct DNA damage but also involve the disruption of redox homeostasis centered around mitochondria and the activation of immune responses. Mitochondria, as a central hub for cellular...

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Detalhes bibliográficos

Principais autores:	Jiamin Guo, Qing Xin, Zheran Liu, Shuang Dai, Jiacheng Li, Yu Min, Zhigong Wei, Yuzhu Hu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-06-01
coleção:	Frontiers in Cell and Developmental Biology
Assuntos:	immunogenic cell death mitochondria radiotherapy Radiotherapy–immunotherapy synergy reactive oxygen species
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fcell.2026.1861854/full
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